WebApr 13, 2024 · Excessive cytotoxic lipofuscin bisretinoid accumulation in the eye is thought to be among the main causes behind the pathogenesis of Stargardt disease, and possibly behind the progression of age-related macular degeneration (AMD). These bisretinoid compounds are part of the visual cycle, which are delivered to the retina by a retinol … WebSep 17, 2024 · Pan-cancer RBP-ncRNA circuits reveal novel miRNA function. Having proved that the abnormal RBP-ncRNA network is functionally related to cancers and useful in clinical application, it would be natural to identify the common RNCs that are dysregulated in multiple tumor types.
Down-regulation of RBP4 indicates a poor prognosis and …
WebJul 8, 2024 · Cancer is the second leading cause of death globally. Abnormity in gene expression regulation characterizes the trajectory of tumor development and progression. … WebEntrepreneur and technical director with extensive experience in precision medicine and in the development of diagnostic molecular tests. After pursuing an academic career with projects focused on Oncology Biomarkers, served as co-founder and technical director of IdenGene Medicina Diagnóstica, the first Brazilian laboratory dedicated to hereditary and … simple projects in physics
Predicting RBP Binding Sites of RNA With High-Order Encoding …
WebJul 30, 2024 · Given the crucial roles that mRNA-RBP interactions (alongside various ncRNAs) play in maintaining proper levels, timing and localisation of gene products, there can be dire consequences when this process is perturbed [].The disruption of this careful balance can lead to aberrant gene expression, which in turn can contribute to prominent … WebApr 11, 2024 · Introduction. RAS genes are among the most mutated proto-oncogenes in human cancers, with around 20% of all malignancies estimated to harbor oncogenic mutations in one of the three highly homologous KRAS, NRAS, or HRAS genes (Prior et al, 2024).The encoded RAS proteins are small GTPases which function as molecular … http://www.epibiotek.com/news_out/detail/322/ ray bernstein obituary